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Knicks vs 76ers Prediction 12/19/25 NBA Picks Today

Philadelphia 76ers (14-11) vs. NY Knicks (19-7)
December 19, 2025 7:00 pm EDT
The Line: NY Knicks -5.5; Over/Under: 229.5
(Get latest betting odds)

The Philadelphia 76ers and NY Knicks meet Friday in NBA action at Madison Square Garden. Here’s a Knicks vs 76ers Prediction. This article will include a Knicks vs 76ers Pick.

Philadelphia 76ers Betting Preview

The Philadelphia 76ers beat the Pacers, lost to the Hawks, and they play the Mavs next. The 76ers have won 5 of their last 8 games.

The Philadelphia 76ers are averaging 116.9 points on 45.6 percent shooting and allowing 116.1 points on 46.4 percent shooting. Tyrese Maxey is averaging 31.5 points and 7.2 assists, while Joel Embiid is averaging 18.2 points and 5.6 rebounds. Kelly Oubre Jr. is the third double-digit scorer and Quentin Grimes is grabbing 4 rebounds. The Philadelphia 76ers are shooting 36.2 percent from beyond the arc and 81.5 percent from the free-throw line. The Philadelphia 76ers are allowing 34.3 percent shooting from deep and are grabbing 45 rebounds per game.

NY Knicks Betting Preview

The NY Knicks beat the Pacers and Spurs, and they play the Heat next. The Knicks have won 18 of their last 22 games.

The NY Knicks are averaging 121 points on 48.1 percent shooting and allowing 112.2 points on 46 percent shooting. Jalen Brunson is averaging 28.8 points and 3.1 rebounds, while Karl-Anthony Towns is averaging 22.4 points and 3.2 assists. Mikal Bridges is the third double-digit scorer, and OG Anunoby is dishing 2 assists. The NY Knicks are shooting 37.8 percent from beyond the arc and 79.5 percent from the free-throw line. The NY Knicks are allowing 36.2 percent shooting from deep and are grabbing 45.9 rebounds per game.

Why the New York Knicks will win

  • The Knicks have won each of their last 10 games as home favorites against Atlantic Division opponents.
  • The 76ers have lost 15 of their last 16 road games against teams that held a winning record.
  • The Knicks have covered the spread in 14 of their last 15 games at Madison Square Garden.
  • The 76ers have failed to cover the spread in each of their last five games as underdogs against opponents who are on the second leg of a back-to-back.

Why the Philadelphia 76ers will win

  • The 76ers have won seven of their last eight games following a loss.
  • The Knicks have lost three of their last four home games on the second leg of a back-to-back against the 76ers.
  • The 76ers have covered the spread in each of their last seven games against the Knicks following a road loss.
  • The Knicks have failed to cover the spread in 14 of their last 18 games on the second leg of a back-to-back against Eastern Conference opponents.

Total Points Facts

  • Fourteen of the 76ers’ last 16 games as underdogs following a road loss have gone OVER the total points line.
  • Each of the Knicks’ last four home games against Eastern Conference opponents have gone UNDER the total points line.

Matchup/League Facts

  • The Knicks rank 1st in the league for opponent offensive rebounds per game this season (10.0).
  • The Knicks rank 2nd in the league for opponent steals per game this season (6.9).
  • The 76ers rank 1st in the league for blocks per game this season (6.2).
  • The 76ers have suffered the equal-largest comeback loss from a HT lead this season – led by 19 points vs Bulls on November 4.

Knicks vs 76ers Injury Report

The Knicks will be without Landry Shamet and Miles McBride. Josh Hart, Mitchell Robinson, and Karl-Anthony Towns are questionable.

The 76ers will be without Kelly Oubre Jr. and Trendon Watford. Joel Embiid is questionable.

Knicks vs 76ers Prediction

It would be nice to know if Embiid was playing, but I’m still going to grab the points with the 76ers. The Knicks have had a week, as they won the NBA Cup, guys got banged up, and they had a walk-off win last night. Now the Knicks have to travel back to NY and get ready for another game. Tough spot against a 76ers team that’s had 5 days of rest.

There’s also questions if KAT, Hart, and Mitchell will be available. That Knicks starting five last night was awful. The Knicks keep winning and cashing tickets, but the schedule spot heavily favors the 76ers. Give me the points.

Randy Chambers's Free Pick: Philadelphia 76ers +5.5

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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