NBA Picks
Philadelphia 76ers vs Detroit Pistons Prediction 10/25/26 NBA Picks Today
Detroit Pistons (2-0) vs. Philadelphia 76ers (3-0)
October 25, 2026 7:30 pm EDT
The Line: Philadelphia 76ers -2.5; Over/Under: 226.5
(Get latest betting odds)
The Detroit Pistons invade the Xfinity Mobile Arena to battle the Philadelphia 76ers on Sunday night.
Detroit Pistons Betting Preview
The Detroit Pistons have stormed out of the gates with two impressive wins in a row and they will be eager to stay undefeated after making light work of the new-look Heat in a 128-111 road win on Friday. John Collins led the team with 23 points on nine of 15 shooting, Paul Reed added 19 points with 11 rebounds on eight of 11 shooting while Duncan Robinson chipped in with 17 points. As a team, the Pistons shot 53 percent from the field and 18 of 38 from the 3-point line as they stormed out of the gates with 41 points in the first quarter to take a 12-point lead into halftime, before they poured in another 38 points in the third quarter to put the game to bed early.
Philadelphia 76ers Betting Preview
Meanwhile, the Philadelphia 76ers are now gunning for a fourth straight victory after running past the Bucks in a 127-116 home win last night. Joel Embiid led the team with a triple-double of 28 points with 11 rebounds and 10 assists, Jaylen Brown added 27 points with five assists while Tyrese Maxey chipped in with 26 points on nine of 22 shooting. As a team, the 76ers shot just 41 percent from the field, but they nailed 19 of 44 shots from the 3-point line and 28 of 34 from the free throw line. LeBron James sat out the game due to back soreness but is expected to return for the second game of a back to back set.
Detroit v Philadelphia Free Prediction
The Pistons have ruled out Jalen Duren again and they are keeping an eye on Ausar Thompson who is listed as questionable with an ankle sprain, while the 76ers have ruled out Tacko Fall and Jabari Walker with Joel Embiid being rested but they do expect to have LeBron James back in action. Both teams will be missing a key player which even things out a bit, but the 76ers are deserved favorites at home. We should be in for a close contest here, but it;s hard to go past the 76ers to get the job done behind big games from James and Brown.



