Memphis Grizzlies (9-12) vs. San Antonio Spurs (13-6)
December 2, 2025 8:00 pm EDT
The Line: San Antonio Spurs -5.5; Over/Under: 231.5
(Get latest betting odds)
The Memphis Grizzlies travel to the Frost Bank Center to take on the San Antonio Spurs on Tuesday night. Here’s a Spurs vs Grizzlies Prediction. This article will include a Spurs vs Grizzlies Pick.
Memphis Grizzlies Betting Preview
The Memphis Grizzlies have been on a nice run as they’ve won five of their last six games overall and they will be gunning for a season-high fourth straight victory after beating the Kings in a 115-107 road win on Sunday. Zach Edey led the team with a monster game of 32 points with 17 rebounds and five blocks on 16 of 20 shooting. Cam Spencer added 16 points with four assists off the bench while Jaren Jackson Jr chipped in with 13 points with six rebounds and five assists. As a team, the Grizzlies shot 52 percent from the field and nine of 24 from the 3-point line as they looked to be in a bit of trouble after scoring just 21 points in the third quarter to fall behind. Before they opened the fourth quarter with a pivotal 11-0 run to take the lead for good.
San Antonio Spurs Betting Preview
Meanwhile, the San Antonio Spurs have been in fine form as they’ve won five of their last seven games overall. They will be eager to bounce back here after having their two-game win streak snapped by the Timberwolves in a 125-112 road defeat on Sunday. De’Aaron Fox led the team with 25 points on 10 of 15 shooting, Devin Vassell and Keldon Johnson each scored 22 points while Dylan Harper chipped in with 17 points on eight of 12 shooting. As a team, the Spurs shot 52 percent from the field and eight of 33 from the 3-point line as they set the tone with 37 points in the first quarter to lead for most of the contest. Before their hard came undone in the fourth quarter where the Spurs got outscored by 36-19 to lose by double digits. The Spurs could’ve done with more from Harrison Barnes who had a rough game and finished with just five points on two of nine shooting.
Why the San Antonio Spurs will win
- The Grizzlies have lost each of their last 17 games against Western Conference opponents that held a winning record.
- The Spurs have won each of their last seven games against Southwest Division opponents.
- The Grizzlies have failed to cover the spread in each of their last six games against Western Conference opponents that held a winning record.
- The Spurs have covered the spread in eight of their last nine games following a road loss.
Why the Memphis Grizzlies will win
- The Grizzlies have won each of their last 10 games against the Spurs following a win.
- The Spurs have lost three of their last four games as favorites on the first leg of a back-to-back.
- The Grizzlies have covered the spread in each of their last six games against the Spurs following a road win.
- The Spurs have failed to cover the spread in eight of their last 10 games against Southwest Division opponents that held a losing record.
Total Points Facts
- Each of the Spurs’ last seven night games on the first leg of a back-to-back have gone OVER the total points line.
- Each of the Grizzlies’ last six road games following a road win have gone UNDER the total points line.
San Antonio Spurs Player Facts
- Keldon Johnson ranks 1st amongst qualified Guards for FG% (57.8%) this season.
- Devin Vassell is one of only 15 qualified players in the league to be leading their team in points (15.9) and assists (2.4) per game this season.
Memphis Grizzlies Player Facts
- Cam Spencer has recorded six games with 3+ assists and zero turnovers this season – equal-most of any player in the league.
- Zach Edey has recorded 13+ rebounds in three consecutive appearances – longest active streak of any player in the league.
Matchup/League Facts
- The Spurs have missed the playoffs in six consecutive seasons – second-longest active streak in the NBA.
- The Spurs are one of three teams to rank in the top-10 for both field goal percentage and free throw percentage this season.
- The Grizzlies rank 1st in the league for opponent free throws made per game this season (16.1).
- Seven different Grizzlies players have scored 25+ points in a game this season – equal-most in the league.
Spurs vs Grizzlies Prediction
The Grizzlies are still missing Brandon Clarke, Scotty Pippen Jr, Ty Jerome and Ja Morant, while the Spurs have ruled out Victor Wembenyama, Jordan McLaughlin and Stephon Castle once again. The Grizzlies have been able to slowly turn things around with five wins from their past six games despite missing a bunch of key players. You could almost say the same about the Spurs who were building nicely before they ran into the Timberwolves in their last outing. It’s tempting to take the Grizzlies with the points in what could be a close one, but I don’t expect Zach Edey to score 32 points again. The Spurs have won eight of their 10 home games this season and I think they build on that impressive record with another win in this one.
