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Arizona Cardinals vs LA Rams Prediction 9-15-24 NFL Picks

LA Rams (0-1) vs. Arizona Cardinals (0-1)
September 15, 2024 4:05 pm EDT
The Line: Arizona Cardinals -1.5; Over/Under: +48.5
(Get latest betting odds)

In this article, we will formulate an Arizona Cardinals vs LA Rams prediction for this NFL game on Sunday, September 15th at State Farm Stadium in Glendale, Arizona. Let’s take a look at the prediction for this week two matchup.

Arizona Cardinals Betting Preview

The Arizona Cardinals are 0-1 this year after they lost to Buffalo by a score of 34-28 in their first game. Arizona led 17-3 in the second quarter, but they allowed the next 21 points to lose the lead. The fourth quarter was very back and forth, but Arizona came up just short in the game. The Cardinals were outgained by a total of 352-270, tied the turnover battle at one, and went 7-13 on third down in the game. Kyler Murray threw for 162 yards and one touchdown, while also rushing for 57 yards. Greg Dortch was the leading receiver, as he caught six passes for 47 yards in the loss. 


I thought Arizona played very well in their first game of the season and even though they lost, I am encouraged by what I saw. The Cardinals defense can definitely be better and I know they had a special teams touchdown, but going on the road and only losing by six against one of the better teams in the AFC is an accomplishment. 

LA Rams Betting Preview

The Los Angeles Rams are 0-1 this season after they lost to Detroit by a score of 26-20 in overtime. Los Angeles trailed 17-3 in the third quarter, but they took a 20-17 lead in the fourth, before giving up the game-tying field goal with 17 seconds left. In overtime, the Lions won the toss and ran the ball all over the LA defense in the loss. The Rams outgained Detroit by a total of 387-363, tied the turnover battle at one, and went 5-12 on third down in the game. Matthew Stafford threw for 317 yards, one touchdown, and one interception, while Kyren Williams rushed for 50 yards and one score on 18 carries. 

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Los Angeles didn’t look very strong on offense in the first half against Detroit, but they turned things up in the second half and nearly walked away with a win. Stafford looked good and he was making some incredible throws, so I have good feelings about this Rams offense, even with Nacua dealing with an injury. 

Why the Rams will beat the Cardinals

  • The Rams have won each of their last nine games at State Farm Stadium.
  • The Cardinals have lost each of their last eight games against NFC West opponents on a winning streak.
  • The Rams have covered the spread in each of their last nine games at State Farm Stadium.
  • The Cardinals have failed to cover the spread in 10 of their last 11 games as home favorites against NFC West opponents.
  • The Rams have scored the first touchdown in nine of their last 10 games at State Farm Stadium.
  • The Rams have won the first quarter in each of their last four September games as road underdogs against NFC opponents.
  • The Cardinals have lost the first half in each of their last seven games against NFC opponents.

Total Points Facts

  • Each of the Rams’ last six games after coming off overtime has gone UNDER the total points line.
  • Each of the Cardinals’ last six games at State Farm Stadium following a loss have gone OVER the total points line.
  • Eight of the last nine Sunday games at State Farm Stadium have gone OVER the total points line.

Arizona Cardinals Player Prop Facts

  • James Conner has scored the first touchdown in three of his last four Week 2 home appearances.
  • Kyler Murray has recorded 35+ rushing yards in each of the Cardinals’ last four games as favorites against NFC West opponents.
  • James Conner has scored at least one touchdown in each of the Cardinals’ last six games.
  • Elijah Higgins has recorded 12+ receiving yards in each of the Cardinals’ last seven games.
  • Kyler Murray has recorded 230+ passing yards in each of his last six September appearances against NFC opponents.
  • James Conner has recorded 83+ rushing and receiving yards in each of the Cardinals’ last six Sunday games.
  • Kyler Murray has thrown two or more touchdowns in three of the Cardinals’ last four September games as home favorites.
  • Kyler Murray has recorded 22+ completions in each of his last 10 regular season appearances against NFC West opponents.
  • Jalen Thompson is just one away from 10 career interceptions.

Los Angeles Rams Player Prop Facts

  • Cooper Kupp has scored at least one touchdown in each of his last eight September appearances.
  • Cooper Kupp has recorded 78+ receiving yards in each of his last six appearances with the Rams as underdogs on the West Coast.
  • Kyren Williams has recorded 61+ rushing yards in eight of his last nine appearances.
  • Kyren Williams has scored two touchdowns in three of his last four appearances against NFC West opponents.
  • Matthew Stafford has recorded 294+ passing yards in each of his last four Sunday road appearances.
  • Cooper Kupp has recorded 78+ rushing and receiving yards in each of his last six appearances with the Rams as underdogs on the West Coast.
  • Kyren Williams has scored the first touchdown in three of his last four appearances following a road loss.
  • Matthew Stafford has recorded 24+ completions in each of his last six appearances against NFC opponents.
  • Matthew Stafford has thrown two or more touchdowns in each of his last five Week 2 road appearances.
  • John Johnson ranks T1st in the NFL in interceptions (1) this season.

Matchup/League Facts

  • The Cardinals rank 32nd in the NFL in H2 opponent points per game (24.0) this season.
  • The Cardinals rank T1st in the NFL in Q1 win percentage (100.0) this season.
  • The Rams rank T1st in the NFL in Q1 win percentage (100.0) this season.
  • The Rams rank T1st in the NFL in Q4 win percentage (100.0) this season.

Arizona Cardinals vs LA Rams Prediction 

The Cardinals come into this game after a very strong effort in Buffalo last weekend and they are a small favorite in this matchup. Los Angeles also played very well in their week one loss and nearly beat a very good Detroit team. I think we could see plenty of points in this game, as I don’t really trust the Arizona defense, but I am siding with the Rams on the road. I was really impressed with Stafford and he should have a very solid game against this defense. Take the Rams to get the win. 

David Racey's Free Pick: Rams ML

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David Racey

David started writing about sports in 2015, but sports has been his passion for as long as he can remember. David spends most of his free time watching pretty much anything sports related from Baseball to Tennis and everything in between. David likes to analyze statistics and recent results to form an unbiased opinion on whatever game he is breaking down. Follow David on Twitter at @itsyerboi41

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