NY Giants (1-0) vs. LA Rams (0-1)
September 21, 2026 8:15 pm EDT
The Line: LA Rams -7; Over/Under: 47.5
(Get latest betting odds)
The New York Giants and Los Angeles Rams meet Monday in NFL action at SoFi Stadium. Here’s a Rams vs. Giants Prediction. This article will include a Rams vs. Giants Pick.
New York Giants Betting Preview
The New York Giants beat the Cowboys, and they play the Titans next. The New York Giants look for their first 2-0 start since the 2022 season. Jaxson Dart is completing 79.3 percent of his passes for 230 yards, 3 touchdowns, and 0 interceptions. Isaiah Likely and Malik Nabers have combined for 147 receiving yards and 2 touchdowns, while Darnell Mooney has 2 receptions.
The New York Giants’ ground game is averaging 165 yards per contest, and Cam Skattebo leads the way with 81 yards and 1 touchdown. Defensively, New York is allowing 20 points and 244 yards per game. Tremaine Edmunds leads the New York Giants with 8 tackles, Deonte Banks has 2 pass deflections, and Jevon Holland has 1 interception.
Los Angeles Rams Betting Preview
The Los Angeles Rams lost to the 49ers and play the Broncos next. The Rams look to avoid their second 0-2 start in the last three seasons. Matthew Stafford is completing 60 percent of his passes for 155 yards, 0 touchdowns, and 1 interception. Puka Nacua and Davante Adams have combined for 100 receiving yards on 8 catches, while Kyren Williams has 3 receptions.
The Los Angeles Rams ground game is averaging 122 yards per contest, and Blake Corum leads the way with 54 yards on 10 carries. Defensively, Los Angeles is allowing 27 points and 379 yards per game. Quentin Lake leads the Los Angeles Rams with 10 tackles, Trent McDuffie has 2 pass deflections, and Omar Speights has 1 pass deflection.
Why the Los Angeles Rams will win
- The Giants have lost each of their last nine games against NFC opponents on a losing streak.
- The Rams have won each of their last five Monday games against teams that held a winning record.
- The Rams have covered the spread in each of their last five Monday games against teams that held a winning record.
- The Giants have failed to cover the spread in each of their last four September games against NFC West opponents.
- The Rams have scored the first touchdown in each of their last five games against the Giants.
- The Giants have lost the first quarter in each of their last eight Monday games.
- The Giants have lost the first half in 16 of their last 17 games against NFC West opponents.
Why the New York Giants will win
- The Giants have won each of their last five games as underdogs without Jason Pinnock.
- The Rams have lost each of their last five games against NFC East opponents on a winning streak.
- The Giants have covered the spread in each of their last six Monday games against teams that held a losing record.
- The Rams have failed to cover the spread in each of their last four games.
- The underdogs have won the first quarter in each of the Giants’ last five Week 2 games.
- The Rams have lost the first half in three of their last four games as moderate favorites (-3.5 to -7.0 points).
Total Points Facts
- Each of the Rams’ last six Week 2 games have gone OVER the total points line.
- Each of the Giants’ last four Monday games has gone OVER the total points line.
Los Angeles Rams Player Prop Facts
- Kyren Williams has scored the first touchdown in three of the Rams’ last four regular season games against NFC East opponents.
- Matthew Stafford has recorded 22+ completions in each of his last six Monday regular season appearances with his team as a favorite.
- Matthew Stafford has recorded 251+ passing yards in each of his last eight appearances with his team as a favorite against NFC East opponents.
- Kyren Williams has recorded 72+ rushing yards in each of the Rams’ last five games against NFC East opponents.
- Kyren Williams has recorded 15+ receiving yards in each of the Rams’ last seven games.
- Kyren Williams has scored at least one touchdown in each of the Rams’ last eight September games against NFC opponents.
- Blake Corum has recorded 61+ rushing and receiving yards in each of the Rams’ last five games played on the West Coast.
- Heading into Week 2, Kyren Williams ranks T1st amongst qualified players for catch rate (100.0%) this season.
New York Giants Player Prop Facts
- Cameron Skattebo has scored at least one touchdown in each of his last four appearances.
- Odell Beckham Jr. has recorded 23+ receiving yards in each of his 23 previous appearances with the Giants as road underdogs.
- Jaxson Dart has recorded 230+ passing yards in four of his last five appearances against NFC opponents.
- Jaxson Dart has recorded 20+ completions in four of the Giants’ last five games.
- Tyrone Tracy has recorded 23+ rushing yards in 12 of his last 13 appearances with the Giants as road underdogs.
- Tyrone Tracy has recorded 33+ rushing and receiving yards in each of his last 13 appearances with the Giants as road underdogs.
- Heading into Week 2, Isaiah Likely ranks T1st in the NFL in receiving touchdowns (2) this season.
Matchup/League Facts
- Heading into Week 2, the Rams rank 32nd in the NFL in points per game (7.0) this season.
- Heading into Week 2, the Rams rank T1st in the NFL in 4th down attempts (3) this season.
- Heading into Week 2, the Giants rank 1st in the NFL in 3rd down percentage (81.8%) this season.
- Heading into Week 2, the Giants rank T1st in the NFL in 1st downs (29) this season.
Rams vs Giants Prediction
I expect the Rams to play better now that they’re on US soil and they’ll have Aaron Donald for this game. This is also a tough spot for the Giants after a big win over the Cowboys and now having to fly across the country. However, we’re getting a free touchdown with a Giants team that looked fantastic in their season opener. Dart is playing with confidence, the ground game is working, and that Giants defense looks improved.
It’s just one game, but there were a lot of positives to take from it, and I’m intrigued to see if there’s something there. Myles Garrett is out for the Rams, and Nacua is questionable as he’s missing practices. It just feels like everybody continues to buy into this Rams hype, and these lines are inflated. Give me the free touchdown with the Giants.
