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Washington Commanders vs NY Giants Prediction 9/7/25 NFL Picks Today

NY Giants (3-0) vs. Washington Commanders (0-3)
September 7, 2025 1:00 pm EDT
The Line: Washington Commanders -6; Over/Under: 45.5
(Get latest betting odds)

The New York Giants and the Washington Commanders meet in week 1 NFL action from Northwest Stadium on Sunday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a New York Giants vs. Washington Commanders prediction.

New York Giants Team Preview

The New York Giants enter 2025 coming off a 3–14 season in 2024 that kept them out of the playoffs. Head coach Brian Daboll returns with coordinators Mike Kafka on offense and Shane Bowen on defense. The offseason brought major changes, headlined by the signings of quarterbacks Russell Wilson and Jameis Winston. New York also strengthened the secondary with free-agent additions Jevon Holland and Paulson Adebo and added defensive tackle Roy Robertson-Harris, while cornerback Adoree’ Jackson departed in free agency. In the 2025 NFL Draft, the Giants used the third overall pick on Penn State edge rusher Abdul Carter and traded back into the first round to select Ole Miss quarterback Jaxson Dart at No. 25 to give the Giants their eventual QB2 after the preseason, before rounding out the class on Day 2 and Day 3. With veteran help at quarterback, multiple defensive reinforcements, and continuity on the sideline, the Giants can only go up from here in 2025… Right?

Why the New York Giants will win

  • The road team has won each of the Giants’ last five Week 1 games.
  • The Commanders have lost 10 of their last 13 games as home favorites against NFC East opponents.
  • The road team has covered the spread in each of the Giants’ last five Week 1 games.
  • The Commanders have failed to cover the spread in 11 of their last 13 games as home favorites against NFC East opponents.

New York Giants Player Prop Facts

  • Malik Nabers has scored at least one touchdown in three of the Giants’ last four games.
  • Russell Wilson has recorded 240+ passing yards in each of his last seven September road appearances.
  • Wan’Dale Robinson has recorded 38+ receiving yards in each of the Giants’ last seven Sunday games.
  • Russell Wilson has recorded 10+ rushing yards in 14 of his 15 previous road appearances against NFC East opponents.
  • Russell Wilson has recorded 20+ completions in seven of his last eight September appearances against NFC opponents.
  • Wan’Dale Robinson has recorded 43+ rushing and receiving yards in each of the Giants’ last three games.
  • Malik Nabers led the NFC for targets (170) last season.

Washington Commanders Team Preview

The Washington Commanders enter 2025 after a shocking 12-5 campaign – their best since 1991 – that culminated in an NFC Championship Game appearance, the franchise’s first since that same year. Under first-year head coach Dan Quinn, Washington put together a dramatic turnaround from a 4-13 record in 2023 as rookie quarterback Jayden Daniels, the No. 2 overall pick in the 2024 draft, emerged as a cornerstone for the franchise going forward. Washington upset the top-seeded Detroit Lions in the playoffs before falling to the Philadelphia Eagles in the conference title game. This offseason, second-year general manager Adam Peters continued reshaping the roster on offense. The Commanders traded for All-Pro receiver Deebo Samuel and Pro Bowl left tackle Laremy Tunsil, also using their first-round pick on tackle Josh Conerly Jr. to strengthen the offensive line. They added veteran wideout Michael Gallup while parting with several receivers, including Dyami Brown and Jamison Crowder. Daniels returns as the starting quarterback, supported by power back Brian Robinson Jr., who rushed for nearly 800 yards last season, and veteran Austin Ekeler. Pro Bowl wideout Terry McLaurin remains a top target alongside Samuel. On defense, Washington lost long-time defensive tackle Jonathan Allen but added former first-round pick Javon Kinlaw to reinforce the interior. The team also replaced departed corner Benjamin St-Juste with veteran Jonathan Jones and second-round draft pick Trey Amos in the secondary. With upgrades on both sides of the ball and growing confidence in the quarterback position, Washington hopes that the 2024 season was a sign of things to come and not a flash in the pan.

Why the Washington Commanders will win

  • The Giants have lost each of their last eight games against NFC opponents.
  • The Commanders have won seven of their last eight games.
  • The Giants have failed to cover the spread in seven of their last eight season openers.
  • The Commanders have covered the spread in each of their last four games played on the East Coast.

Washington Commanders Player Prop Facts

  • Terry McLaurin has scored at least one touchdown in eight of the Commanders’ last nine games.
  • Jayden Daniels has recorded 22+ completions in nine of the Commanders’ last 10 games.
  • Austin Ekeler has recorded 25+ rushing yards in 13 of his last 14 September appearances with his team as a favorite.
  • Jayden Daniels has recorded 255+ passing yards in each of the Commanders’ last three games.
  • Austin Ekeler has recorded 53+ rushing and receiving yards in each of his last 21 September appearances.
  • Austin Ekeler has recorded 31+ receiving yards in each of his last 11 September home appearances.
  • Jayden Daniels recorded the equal-most passing touchdowns in a single game last season (5 vs Eagles, Week 16).

Total Points Facts

  • Each of the Giants’ last eight September games as underdogs have gone UNDER the total points line.
  • Each of the Commanders’ last five home games have gone OVER the total points line.
  • Six of the last eight Sunday games at Northwest Stadium have gone OVER the total points line.

New York Giants vs. Washington Commanders Prediction

I’m on the Giants and the points here. Despite their shortcomings in 2024, the Giants played the Commanders tough, holding Washington to 7 field goals in a 3-point win early on and battling just as hard in the rematch. All in all, I think this is going to be another battle that could be even more competitive just because of the improvements within New York’s roster, especially at QB. Give me the Giants and the points.


Chris Ruffolo

Chris joined the Sports Chat Place team in August 2016 and has a proven system that combines multiple analytical and situational statistics and trends to give out thousands of winning picks over the last three years with winning records across all of the top leagues, Follow Chris Ruffolo on Twitter @ruffthepickdawg

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