San Francisco 49ers vs Detroit Lions Prediction 12-30-24 NFL Picks

In this article, we will formulate a San Francisco 49ers vs Detroit Lions prediction for this NFL game on Monday, December 30th at Levi’s Stadium in Santa Clara, California. Let’s take a look at the prediction for this week 17 matchup.

San Francisco 49ers Betting Preview

The San Francisco 49ers are 6-9 this year after they lost to Miami by a score of 29-17 in their last game. San Francisco cut the deficit to 19-17 early in the fourth quarter, but they allowed the next 10 points and let the game slip away. The 49ers were outgained by a total of 381-374, lost the turnover battle 1-0, and went 5-13 on third down in the game. Brock Purdy threw for 313 yards, two touchdowns, and one interception, while George Kittle caught eight passes for 106 yards in the game. 

Prior to that loss, the 49ers lost to the Rams by a score of 12-6 but did beat the Bears by a score of 38-13 before that. The SF offense has scored 22.1 points per game with 235.7 passing yards and 130 rushing yards per game, while the defense has allowed 23.3 points per game this season. Brock Purdy has completed 65% of his passes for 3,487 yards, 17 touchdowns, and 10 interceptions, while George Kittle has caught 68 passes for 967 yards and eight scores. 

Detroit Lions Betting Preview

The Detroit Lions are 13-2 this season after they defeated Chicago by a score of 34-17 in their last game. Detroit led 20-0 in the second quarter and they cruised to the win in the second half. The Lions outgained Chicago by a total of 475-382, won the turnover battle 2-0, and went 7-12 on third down in the game. Jared Goff threw for 336 yards and three touchdowns, while Jameson Williams caught five passes for 143 yards and one score in the win. 

Prior to that game, the Lions lost to the Bills by a score of 48-42 but did win the 11 games before that. The Detroit offense has scored 32.9 points per game with 264.7 passing yards and 143.9 rushing yards per game, while the defense has allowed 19.9 points per game this season. Jared Goff has completed 71.4% of his passes for 4,095 yards, 33 touchdowns, and 10 interceptions, while Amon-Ra St. Brown has caught 101 passes for 1,126 yards and 11 scores this year. 

Why the Lions will beat the 49ers

• The Lions have won each of their last eight games against NFC opponents.
• The 49ers have lost five of their last six games.
• The Lions have covered the spread in each of their last eight road games against NFC opponents.
• The 49ers have failed to cover the spread in each of their last six home games against teams that held a winning record.
• The Lions have scored the first touchdown in each of their last seven games as favorites against NFC opponents.
• The Lions have won the first half in each of their last nine games as road favorites against NFC opponents.
• The road team has won the first quarter in each of the last four games between the Lions and 49ers.

Total Points Facts

• Nine of the Lions’ last 10 December games as favorites have gone OVER the total points line.
• Eight of the 49ers’ last nine games following a loss have gone OVER the total points line.

San Francisco 49ers Player Prop Facts

• Russell Gage has scored the last touchdown in three of his last four regular-season appearances with his team as an underdog.
• Brock Purdy has recorded 252+ passing yards in each of his five previous appearances against NFC North opponents.
• Deebo Samuel has recorded 47+ receiving yards in each of his last seven Monday appearances.
• Deebo Samuel has recorded 13+ rushing yards in each of his last four appearances with the 49ers as underdogs on the West Coast.
• Joshua Dobbs has scored a touchdown in each of his last five appearances with his team as an underdog.
• Deebo Samuel has recorded 60+ rushing and receiving yards in each of his last five appearances with the 49ers as underdogs in California.
• Brock Purdy has thrown two or more touchdowns in eight of the 49ers’ last nine December games against NFC opponents.
• Heading into Week 17, Jauan Jennings has recorded the equal-most receiving touchdowns in a single game this season (3 vs Rams, Week 3).

Detroit Lions Player Prop Facts

• Jared Goff has recorded 257+ passing yards in each of the Lions’ last six December games.
• David Montgomery has recorded 20+ receiving yards in each of the Lions’ last seven games as favorites following a win.
• David Montgomery has scored the first touchdown in five of his six previous December appearances with his team as a favorite against NFC opponents.
• Jared Goff has recorded 10+ rushing yards in each of his last four regular-season appearances against the 49ers.
• Amon-Ra St. Brown has scored a touchdown in each of the Lions’ last seven regular season road games against NFC opponents.
• David Montgomery has recorded 70+ rushing and receiving yards in each of his last 10 appearances against NFC opponents.
• Jared Goff has thrown two or more touchdowns in each of the Lions’ last six games following a road win.
• Jared Goff has recorded 23+ completions in each of the Lions’ last five December games as favorites.
• Heading into Week 17, Kerby Joseph ranks T1st in the NFL in interceptions (7) this season.

Matchup/League Facts

• Heading into Week 17, the 49ers rank 2nd in the NFL in yards allowed per game (304.3) this season.
• Heading into Week 17, the 49ers rank 31st in the NFL in total punt yards (1976) this season.
• Heading into Week 17, the Lions rank 1st in the NFL in points per game (32.9) this season.
• Heading into Week 17, the Lions rank 1st in the NFL in punt return yards per game (30.4) this season.

San Francisco 49ers vs Detroit Lions Prediction 

Detroit comes into this matchup still controlling their own destiny for the one seed in the NFC, but they could lock it up with a win here and a Minnesota loss against Green Bay. The Lions continue to have the best scoring offense in the NFL, but their defense is a big question mark, especially with all of their injuries. San Francisco has had a disappointing season and they have lost five of their last six games, but they are 4-4 at home this year. We have seen this 49ers defense allow at least 29 points in three of their last five games, which is a concern against this Lions offense. This will probably be a higher-scoring game with neither defense playing very well, but I like the Lions offense to make a few more plays and get the cover.