Brewers vs Cardinals Prediction 5/27/26 MLB Picks Today

The St. Louis Cardinals and Milwaukee Brewers meet on Wednesday in MLB action at American Family Field. Here’s a Brewers vs Cardinals Prediction. This article will include a Brewers vs Cardinals Pick.

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 29-24 on the year and play the Cubs and Rangers next. The St. Louis Cardinals are batting .238 on the season, with a .318 OBP and a .384 slugging percentage. The St. Louis Cardinals’ pitching staff has a 4.27 ERA and a 1.39 WHIP. Jordan Walker leads the St. Louis Cardinals with 59 hits and 42 RBI, while Alec Burleson and Ivan Herrera have combined for 110 hits and 61 RBI.

Dustin May gets the ball for the St. Louis Cardinals, and he is 3-5 with a 5.00 ERA and 42 strikeouts this season. This will be May’s second career game against the Milwaukee Brewers.

Milwaukee Brewers Betting Preview

The Milwaukee Brewers are 32-20 on the year and play the Giants and Astros next. The Milwaukee Brewers are batting. 249 on the season, have a .335 OBP, and have a .368 slugging percentage. The Milwaukee Brewers’ pitching staff has a 3.19 ERA and a 1.19 WHIP. William Contreras leads the Milwaukee Brewers with 60 hits and 33 RBI, while Brice Turang and Jake Bauers have combined for 98 hits and 60 RBI.

The Milwaukee Brewers didn’t announce a starting pitcher at the time this article was published.

Why the Milwaukee Brewers will win

• The Brewers have won each of their last six games against NL Central opponents.
• The Cardinals have lost seven of their last eight games against NL Central opponents following a road loss.
• The Brewers have covered the run line in each of their last seven day games against NL Central opponents that held a winning record.
• The Cardinals have failed to cover the run line in each of their last five games against NL Central opponents following a road loss.
• The Brewers have led after 5 innings in each of their last eight games as home favorites.
• The Brewers have won the first inning in four of their last five games as favorites against National League opponents.
• The Brewers have led after 3 innings in eight of their last nine games against opponents that held a winning record.

Why the St. Louis Cardinals will win

• The Brewers have lost three of their last four games as favorites against the Cardinals following a win.
• The Cardinals have won eight of their last 11 games as road underdogs following a loss.
• The Brewers have failed to cover the run line in eight of their last nine games against the Cardinals following a win.
• The Cardinals have covered the run line in each of their last seven Wednesday games as road underdogs against NL Central opponents.

Total Runs Facts

• Each of the Cardinals’ last seven road games after playing the previous day has gone UNDER the total runs line.
• Each of the Brewers’ last four games as favorites has gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in six of the Cardinals’ last seven road games against National League opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in five of the Brewers’ last six day games.

Matchup/League Facts

• The Brewers rank 30th in the league for home runs this season (35).
• The Brewers rank 1st in the league for home runs allowed this season (37).
• The Cardinals rank 29th in the league for strikeouts this season (392).
• The Cardinals rank T28th in the league for triples this season (3).

Brewers vs Cardinals Prediction

The Brewers didn’t announce a starting pitcher, but who cares? The Brewers are playing better baseball. Also, May has been a disaster this season with a 5.00 ERA and 1.43 WHIP. In 20.2 road innings, May has a 5.23 ERA and a .291 allowed batting average. It’s also a quick turnaround, which usually favors the home team. I don’t care who the Brewers throw out there; I’m riding with the home team on Wednesday afternoon.