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Brewers vs Tigers Prediction 4/16/25 MLB Picks Today

Detroit Tigers (10-7) vs. Milwaukee Brewers (9-9)
April 16, 2025 1:10 pm EDT
The Line: Milwaukee Brewers -148 / Detroit Tigers 124; Over/Under: 8.5
(Get latest betting odds)

In this article we will formulate a Brewers vs Tigers prediction for this MLB game on Wednesday, April 16th at American Family Field in Milwaukee, Wisconsin. Let’s take a look at the prediction for this MLB matchup. 

Milwaukee Brewers Betting Preview

The Milwaukee Brewers are 9-9 this year and they have lost three of their last four games. Milwaukee lost the first game in this series by a score of 9-1, but they did bounce back with a 5-0 win in game two. In that victory, the Brewers scored two runs in the second inning and they continued to pull away in the rest of the game for the win. Milwaukee recorded nine hits in the game and they were led by Hoskins, who went 3-4 with one home run and two RBIs in the win. Milwaukee started Priester, who allowed just one hit over 5.0 innings in the win, while Koenig, Uribe, Mears, and Anderson combined to allow zero hits the rest of the way. 


Prior to this series, the Brewers lost two out of three against the Diamondbacks and won two out of three against the Rockies. The Milwaukee pitching staff has a 4.65 ERA with a 1.33 WHIP and a .232 opponent batting average, while the offense has scored 87 runs with a .233 batting average and a .307 on base percentage this season. Jackson Chourio has led Milwaukee with five home runs and 17 RBIs, while William Contreras has added three home runs and 11 RBIs this year. The projected starting pitcher for Milwaukee is Jose Quintana, who is 1-0 with a 0.00 ERA and a 0.57 WHIP over 7.0 innings pitched this year. 

Detroit Tigers Betting Preview

The Detroit Tigers are 10-7 this season and they have won three of their last five games. In that game two loss, the Tigers fell behind early in the game and never had a chance to get back into it. The Tigers recorded just one hit and they committed one error in the game, while they were led by Torres, who had their lone hit in the loss. Detroit started Flaherty, who allowed five hits and three earned runs over 4.2 innings in the loss, while Hanifee allowed three hits in 1.1 relief innings. 

Prior to this series, the Tigers won two out of three against the Twins and two out of three against the Yankees. The Detroit pitching staff has a 3.40 ERA with a 1.12 WHIP and a .211 opponent batting average, while the offense has scored 80 runs with a .239 batting average and a .317 on base percentage this season. Spencer Torkelson has led Detroit with five home runs and 12 RBIs, while Kerry Carpenter has added five home runs and 10 RBIs this year. The projected starting pitcher for Detroit is Keider Montero, who was just called up and is making his first start of the season. 

Why the Brewers will beat the Tigers

  • The Brewers have won each of their last eight games against AL Central opponents following a home win.
  • The Tigers have lost each of their last four day games against National League opponents.
  • The Brewers have covered the run line in four of their last five games as favorites.
  • The Tigers have failed to cover the run line in four of their last five games against National League opponents after playing the previous day.
  • The Tigers have trailed after 3 innings in each of their last four day games against National League opponents.
  • The Tigers have trailed after 5 innings in 11 of their last 13 games as road underdogs against NL Central opponents.

Why the Tigers will beat the Brewers

  • The Tigers have won six of their last seven games as road underdogs against NL Central opponents following a road loss.
  • The Brewers have lost each of their last five day games against teams that held a winning record.
  • The Tigers have covered the run line in each of their last 10 Wednesday games as underdogs.
  • The Brewers have failed to cover the run line in each of their last six games against the Tigers following a win.
  • The Brewers have lost the first inning in four of their last five day games against American League opponents.
  • The Brewers have trailed after 3 innings in six of their last seven day games against opponents that held a winning record.
  • The Brewers have trailed after 5 innings in six of their last seven day games against opponents that held a winning record.

Total Runs Facts

  • Five of the Tigers’ last six day games after playing the previous day have gone UNDER the total runs line.
  • Five of the Brewers’ last six games as favorites against AL Central opponents have gone UNDER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Tigers’ last six games as underdogs against NL Central opponents.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in nine of the Brewers’ last 10 day games.

Milwaukee Brewers Player Prop Facts

  • Rhys Hoskins has hit a home run in each of his last two appearances with his team as a home favorite against the Tigers.
  • William Contreras has recorded at least one RBI in seven of the Brewers’ last eight games.
  • Jose Quintana has recorded six or more strikeouts in four of his last five home appearances against AL Central opponents that held a winning record.
  • Jackson Chourio has scored at least one run in each of the Brewers’ last six games as favorites.
  • Sal Frelick has recorded at least one Single in each of the Brewers’ last six day games against AL opponents that held a winning record.
  • Christian Yelich has recorded at least one hit in each of his last 10 home appearances against AL opponents that held a winning record.
  • Jose Quintana has recorded a win in three of his last four appearances with his team as a favorite .

Detroit Tigers Player Prop Facts

  • Spencer Torkelson has hit a home run in three of the Tigers’ last four day games.
  • Spencer Torkelson has scored at least one run in each of the Tigers’ last four day games.
  • Manuel Margot has recorded at least one Single in each of his last five appearances with his team as an underdog against NL opponents.
  • Manuel Margot has recorded an RBI in each of his last four road appearances against NL opponents.
  • Gleyber Torres has recorded a Double in three of his last four appearances against NL Central opponents at American Family Field.
  • Gleyber Torres has recorded at least one hit in each of his last 10 appearances against NL Central opponents.

Brewers vs Tigers Prediction 

Detroit has had a very nice start to the season in their first 17 games, but they were shutout on Tuesday night and only managed one hit. The Tigers are 10-4 in their last 14 games, but they have scored one run or fewer in two of their last three. Milwaukee snapped a three game losing streak on Tuesday night, but their pitching staff has allowed at least five runs in three of their last four games. I know Quintana had a very solid first outing for the Brewers, but I don’t really trust either pitcher in this game. Take the over here. 

David Racey's Free Pick: Over 8.5

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David Racey

David started writing about sports in 2015, but sports has been his passion for as long as he can remember. David spends most of his free time watching pretty much anything sports related from Baseball to Tennis and everything in between. David likes to analyze statistics and recent results to form an unbiased opinion on whatever game he is breaking down. Follow David on Twitter at @itsyerboi41

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