Dodgers vs Padres Prediction 8/16/25 MLB Picks Today

The San Diego Padres and the Los Angeles Dodgers meet Saturday in MLB action from Dodger Stadium. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Dodgers vs Padres Prediction.

Starting Pitching Matchup

The San Diego Padres will send out Dylan Cease for the start here and Cease is 5-10 with a 4.52 ERA and 169 strikeouts this season. In his last five starts against the Dodgers, Cease is 2-1 with a 3.86 ERA and 40 strikeouts. The Los Angeles Dodgers will start Blake Snell here and Snell is 2-1 with a 2.37 ERA and 22 strikeouts this season. This will be Snell’s second career starts against the Padres.

San Diego Padres Recap

The San Diego Padres come into this game looking to rebound from their loss at the hands of the Dodgers last time out to sit at 69-53 on the year. After this series, the Padres will head home for a series against the San Francisco Giants.

Padres Have Five-Game Win Streak Snapped

Manny Machado has 138 hits including a team-high 30 doubles, 20 home runs, 72 RBIs and 11 stolen bases while Fernando Tatis Jr. has 120 hits with 17 home runs and 49 RBIs along with 24 stolen bases of his own this season. Luis Arraez has added 136 hits with 23 doubles, 4 triples, 6 home runs and 46 RBIs while Jackson Merrill’s added 91 hits with 9 home runs and 51 RBIs as well. Xander Bogaerts also has 27 doubles and 19 stolen bases as well this season. Gavin Sheets also has 16 doubles, 15 home runs and 54 RBIs as well this season.

Why the San Diego Padres will win

• The Dodgers have lost each of their last five games as home favorites against National League opponents following a win.
• The Padres have won each of their last five games as underdogs after playing the previous day.
• The Padres have covered the run line in 12 of their last 13 games as underdogs.
• The Dodgers have failed to cover the run line in each of their last six home games against National League opponents following a win.

San Diego Padres Player Prop Facts

• Jackson Merrill has recorded a Double in each of the Padres’ last three games as underdogs against NL West opponents.
• Manny Machado has hit a home run in three of the Padres’ last seven night games against NL opponents that held a winning record.
• Dylan Cease has recorded seven or more strikeouts in seven of his last eight appearances against opponents that held a winning record.
• Gavin Sheets has recorded at least one hit in each of his last 11 appearances against NL West opponents that held a winning record.
• Manny Machado ranks 3rd in the league in Hits (138) this season.

Los Angeles Dodgers Recap

The Los Angeles Dodgers come into this game looking to build on their win over the Padres from Friday’s opener to improve to 69-53 this season. After this series, the Dodgers will head on the road for a series against the Colorado Rockies.

Dodgers Snap Four-Game Losing Streak

Shohei Ohtani has 132 hits including 16 doubles, 43 home runs, 80 RBIs and 8 triples while Tommy Edman has 69 hits with 12 home runs and 44 RBIs. Michael Conforto has 61 hits with 18 doubles while Teoscar Hernandez has 96 hits with 19 home runs, 23 doubles and 72 RBIs as well this season. Ohtani has a team-high 17 stolen bases while Max Muncy has 10 doubles but also has 71 strikeouts so far this season. Mookie Betts has also chipped in 12 home runs and 56 RBIs as well on the year. Freddie Freeman has also logged 122 hits with a team-high 29 doubles, 14 home runs and 66 RBIs. Andy Pages also has 122 hits with 20 doubles, 19 home runs and 69 RBIs as well this season.

Why the Los Angeles Dodgers will win

• The Padres have lost each of their last nine Saturday games at Dodger Stadium.
• The Dodgers have won eight of their last nine games against NL West opponents following a home win.
• The Padres have failed to cover the run line in each of their last six Saturday games at Dodger Stadium.
• The Dodgers have covered the run line in each of their last four games as favorites against NL West opponents following a win.

Los Angeles Dodgers Player Prop Facts

• Blake Snell has recorded six or more strikeouts in each of his last nine Saturday appearances with his team as a favorite.
• Teoscar Hernandez has recorded at least one hit in each of the Dodgers’ last eight games against NL West opponents.
• Will Smith has hit a home run in four of his last five appearances against the Padres after playing the previous day.
• Blake Snell has recorded a win in each of his last four appearances against opponents that held a winning record.
• Shohei Ohtani ranks T2nd in the league in Home Runs (43) this season.

Total Runs Facts

• Thirteen of the Padres’ last 14 night games as underdogs have gone UNDER the total runs line.
• Seven of the Dodgers’ last eight games as favorites against NL West opponents have gone UNDER the total runs line.

Dodgers vs Padres Prediction

I’m on the Dodgers in this one. I get the case to be made for either side in this game, but I’m backing the Dodgers because I think the Padres are good enough to get their revenge here. Furthermore, I’m not trusting the Dodgers with Snell on the bump. Snell historically has been a pitcher that takes a while to get going and for a strikeout dependent starter like Snell, facing the Padres won’t help as they take a lot of good at bats. Give me San Diego here.