Reds vs Padres Prediction 6/28/25 MLB Picks Today

The San Diego Padres and Cincinnati Reds meet Saturday in MLB action at Great American Ball Park. Here’s a Reds vs Padres Prediction. This article will include a Reds vs Padres Pick.

San Diego Padres Betting Preview

The San Diego Padres are 44-37 on the year and play the Phillies, Rangers, and Diamondbacks next. The San Diego Padres are batting .246 on the season, have a .314 OBP, and a .376 slugging percentage. The San Diego Padres pitching staff has a 3.64 ERA and a 1.22 WHIP. Manny Machado leads the San Diego Padres with 91 hits and 47 RBI, while Luis Arraez and Fernando Tatis Jr. have combined for 165 hits and 67 RBI.

Randy Vasquez gets the ball for the San Diego Padres, and he is 3-4 with a 3.60 ERA and 45 strikeouts this season. This will be Vasquez’s first career game against the Cincinnati Reds.

Cincinnati Reds Betting Preview

The Cincinnati Reds are 43-39 on the year and play the Red Sox, Phillies, and Marlins next. The Cincinnati Reds are batting .247 on the season, have a .319 OBP, and a .403 slugging percentage. The Cincinnati Reds pitching staff has a 3.81 ERA and a 1.21 WHIP. Elly De La Cruz leads the Cincinnati Reds with 88 hits and 56 RBI, while TJ Friedl and Spencer Steer have combined for 154 hits and 61 RBI.

Andrew Abbott gets the ball for the Cincinnati Reds, and he is 7-1 with a 1.79 ERA and 72 strikeouts this season. Abbott is 1-0 with a 0.61 ERA and 14 strikeouts in his career against the San Diego Padres.

Why the Cincinnati Reds will win

• The Reds have won each of their last 10 home games against NL West opponents that held a winning record.
• The Padres have lost four of their last five road games.
• The Reds have covered the run line in each of their last six games against NL West opponents.
• The Padres have failed to cover the run line in each of their last five games.
• The Reds have won the first inning in each of their last three games as favorites.
• The Reds have led after 3 innings in each of their last three games against NL West opponents that held a winning record.
• The Padres have trailed after 5 innings in each of their last six Saturday day road games.

Why the San Diego Padres will win

• The Padres have won each of their last four games as underdogs against NL Central opponents following a loss.
• The Reds have lost seven of their last eight games against the Padres following a win.
• The Padres have covered the run line in each of their last eight day games against National League opponents following a loss.
• The Reds have failed to cover the run line in seven of their last eight games as favorites following a win.
• The Reds have trailed after 3 innings in five of their last six games as home favorites.
• The Reds have trailed after 5 innings in three of their last four day games against National League opponents that held a winning record.

Cincinnati Reds Player Prop Facts

• Jose Trevino has recorded at least one Double in each of his last three appearances against NL opponents that held a winning record.
• Tyler Stephenson has hit at least one home run in four of his last five appearances with the Reds as favorites against NL West opponents.
• Austin Hays has recorded at least one hit in each of his last nine home appearances.
• Elly De La Cruz ranks T4th in the league in Steals (22) this season.

San Diego Padres Player Prop Facts

• Xander Bogaerts has recorded a Double in four of the Padres’ last five games as underdogs against NL opponents.
• Manny Machado has hit a home run in three of the Padres’ last four games as underdogs against NL Central opponents.
• Jose Iglesias has recorded at least one hit in each of his last 12 appearances in day games against NL Central teams that held a winning record.
• Manny Machado ranks T9th in the league in Hits (91) this season.

Reds vs Padres Prediction

Vasquez has been solid this season with a 3.60 ERA and 1.33 WHIP, and the Padres are better than what they’ve shown lately. However, the Padres have underachieved over the last month, and there are some reasons for concern. The Reds are finally looking like the team we expected to see out of the gate, and Abbott has been ridiculous with his 1.79 ERA and 0.97 WHIP. Abbott has allowed two earned runs in his last 21.2 innings. I’m not stepping in front of Abbott, and it makes it even easier with the Reds playing well as a whole. Give me the Reds.