San Antonio Spurs (16-7) vs. LA Lakers (17-6)
December 10, 2025 10:00 pm EDT
The Line: LA Lakers -4.5; Over/Under: 236.5
(Get latest betting odds)
The Los Angeles Lakers play host to the San Antonio Spurs at the Crypto.com Arena in the NBA Cup on Wednesday night. Here’s a Lakers vs Spurs Prediction. This article will include a Lakers vs Spurs Pick.
San Antonio Spurs Betting Preview
The San Antonio Spurs have been in great shape as they’ve won eight of their last 11 games overall and they will be eager to keep it going after sneaking past the Pelicans in a 135-132 road win on Monday. Harrison Barnes led the team with 24 points on nine of 15 shooting, Dylan Harper added 22 points with six assists on 10 of 16 shooting off the bench while Stephon Castle chipped in with 18 points and five assists. As a team, the Spurs shot 49 percent from the field and 17 of 36 from the 3-point line as they looked to be in trouble after allowing 45 points in the third quarter to squander an early 25-point lead. Before they went on a crucial 13-3 run in the fourth quarter to reclaim the lead for good.
Los Angeles Lakers Betting Preview
Meanwhile, the Los Angeles Lakers have cooled off slightly since their seven-game win streak as they have split their last four games. They will be eager to build some momentum after sneaking past the 76ers in a 112-108 road win on Sunday. Luka Doncic led the team with a triple-double of 31 points with 15 rebounds and 11 assists, LeBron James added 29 points with seven rebounds and six assists while Rui Hachimura chipped in with 17 points. As a team, the Lakers shot 48 percent from the field and 13 of 36 from the 3-point line as they went on a pivotal 23-9 run in the third quarter to climb back into the contest after a slow start. Before they James scored a crucial five points on back to back shots late in the fourth quarter to steal the win in a game looked destined for overtime.
Why the Los Angeles Lakers will win
- The Lakers have won each of their last 13 games against Southwest Division opponents.
- The Spurs have lost each of their last eight games against Pacific Division opponents following a win.
- The Lakers have covered the spread in each of their last eight games against Spurs teams that held a winning record.
- The Spurs have failed to cover the spread in each of their last eight games against Pacific Division opponents following a win.
Why the San Antonio Spurs will win
- The Spurs have won each of their last six Wednesday games as underdogs.
- The Lakers have lost nine of their last 12 home games against Spurs teams that held a winning record.
- The Lakers have failed to cover the spread in each of their last four games following a win.
- The Spurs have covered the spread in each of their last six Wednesday games as underdogs.
Total Points Facts
- Each of the Lakers’ last 10 home games have gone OVER the total points line.
- Each of the Spurs’ last eight Wednesday games as underdogs have gone UNDER the total points line.
Lakers vs Spurs Prediction
The Spurs are still missing Jordan McLaughlin and Victor Wembenyama, while the Lakers currently have Marcus Smart on the injury report, but the word is that he intends to play in this contest. The Spurs are coming into this contest in great shape as they’ve rallied since the injury to Wembenyama, and they will have their eyes on revenge after falling to the Lakers by just 118-116 back on Nov. 5. The Lakers have seen a few bumps in the road lately as they’ve been dealing with injuries and players sitting out, but they are deserved favorites at home. Especially with the news that they could be at full strength for this one. You can make an argument for either side here, but with the line so short, I have to lean towards the Lakers at home, especially because they haven’t played since Sunday.
