Seahawks vs Colts Prediction 12/14/25 NFL Picks Today

The Indianapolis Colts and the Seattle Seahawks meet Sunday in NFL action from Lumen Field in Seattle. Here’s a Seahawks vs Colts prediction. We will look at this from a betting perspective and determine the best Seahawks vs Colts pick.

Indianapolis Colts Betting Preview

The Colts had a great run going into their bye week this year, but things have been shaky since then. Indy won eight of their first 10 games, taking out the Dolphins, Broncos, Titans, Raiders, Cardinals, Chargers, Titans and Falcons among losses to only the Rams and Steelers in that time. After the bye, the Colts lost to the Chiefs and Texans in their next two outings. That would give Indianapolis an 8-4 run across the first dozen games of the season.

On Sunday in their road match with Jacksonville, the Colts coughed up 28 points in the first half alone. Despite scoring in every quarter, Indy limped to a 36-19 loss in the end. QB Riley Leonard was 18-of-29 for 145 yards and a pick, while Jonathan Taylor had 74 yards and a score on 21 carries. Alec Pierce caught five balls for 80 yards in the losing effort as well.

Seattle Seahawks Betting Preview

Over on the Seahawks’ side, they also notched a nice run ahead of their bye this year. Seattle went 5-2 in their first seven outings, falling versus the Bucs and 49ers amid wins over the Steelers, Saints, Cardinals, Jaguars and Texans. Seattle won four of their next five games from there, falling versus the Rams amid wins otherwise versus the Commanders, Cardinals, Titans and Vikings in succession. Through the first dozen games this year the Seahawks put up a nice 9-3 record overall.

Matched up against the Falcons on Sunday, the Seahawks were all tied up at halftime 6-6. Seattle rattled off 31 points from there however, leading to a dominant win 37-9 in the end. QB Sam Darnold was 20-of-30 for 249 yards, three scores and a pick. Leading rusher Zach Charbonnet had seven carries for 46 yards, and Jaxon Smith-Njigba caught seven balls for 92 yards and a pair of scores in the victory effort.

Why the Seattle Seahawks will win

• The Colts have lost each of their last 10 games as underdogs against NFC opponents.
• The home team has won each of the Colts’ last seven Week 15 games.
• The Colts have failed to cover the spread in each of their last seven games as underdogs against NFC opponents.
• The Seahawks have covered the spread in seven of their last eight games.
• The favorites have won the first half in seven of the Seahawks’ last eight games.
• The Seahawks have scored the first touchdown in each of their last six games as favorites.
• The Colts have won the first quarter in two of their last three games as heavy underdogs (>+7.0 points).

Why the Indianapolis Colts will win

• The Colts have won four of their last five games as road underdogs following a Division loss.
• The Seahawks have lost each of their last three December games as home favorites.
• The Seahawks have failed to cover the spread in seven of their last eight Week 15 games.
• The Colts have covered the spread in each of their last four games without Jonathan Taylor.
• The Seahawks have lost the first half in each of their last six home games in December.
• The Colts have scored the first touchdown in each of their last 10 games as road underdogs.
• The Seahawks have lost the first quarter in each of their last six home games in December.

Total Points Facts

• Each of the Colts’ last six games in December have gone OVER the total points line.
• Each of the Seahawks’ last five Week 15 games have gone UNDER the total points line.
• Three of the last four Sunday games at Lumen Field have gone OVER the total points line.

Seattle Seahawks Player Prop Facts

• Zach Charbonnet has scored at least one touchdown in seven of his last eight appearances following a road win.
• Zach Charbonnet has recorded 47+ rushing yards in seven of his last eight appearances following a road win.
• Zach Charbonnet has recorded 44+ rushing and receiving yards in each of his last 12 appearances following a win.
• Sam Darnold has recorded 241+ passing yards in six of his last seven appearances against AFC opponents.
• Zach Charbonnet has recorded 12+ receiving yards in each of the Seahawks’ last seven December games.
• Sam Darnold has recorded 20+ completions in each of his last six December appearances.
• Heading into Week 15, Jaxon Smith-Njigba ranks 1st in the NFL in receiving yards (1428) this season.

Indianapolis Colts Player Prop Facts

• Daniel Jones has recorded 236+ passing yards in five of his last six appearances with his team as a road underdog.
• Josh Downs has recorded 37+ receiving yards in each of his last eight appearances with the Colts as underdogs following a loss.
• Jonathan Taylor has scored at least one touchdown in six of the Colts’ last seven December games.
• Jonathan Taylor has recorded 96+ rushing yards in five of the Colts’ last six December games.
• Jonathan Taylor has recorded 136+ rushing and receiving yards in three of the Colts’ last four games against NFC opponents.
• Daniel Jones has recorded 22+ completions in each of his last six appearances against NFC West opponents.
• Heading into Week 15, Jonathan Taylor ranks 1st in the NFL in rushing yards (1356) this season.

Matchup/League Facts

• Seahawks – six different players have recorded multi-touchdown games this season – equal-most in the NFL, heading into Week 15.
• Seahawks – two different players have recorded 80+ rushing yards in a game this season – equal-most in the NFL, heading into Week 15.
• Heading into Week 15, the Colts rank 32nd in the NFL in total punt yards (1535) this season.
• Heading into Week 15, the Colts have played in the equal-highest number of games that went to overtime this season (2).

Seahawks vs Colts Prediction

I’ll lean toward the Seahawks. Seattle started out slowly last weekend in their win over Atlanta but eventually rolled. The Seahawks offense posted 365 total yards with 6.3 yards per play, 20 first downs and 6-of-13 on third-down tries. Defensively Seattle gave up 274 yards with 4.4 yards per play alongside just 15 first downs and a stellar 1-of-13 on third downs allowed. The three takeaways were nice as well. Seattle has given up just nine combined points over the last two games, so their defense is cooking right now.
As for the Colts, they’ve got a long uphill climb here after losing starting QB Daniel Jones to an Achilles injury last weekend. Indianapolis posted three turnovers and 285 yards (89 rushing) in their latest loss to Jacksonville, which marks the team’s third straight loss. They’ve been below 21 points in each of those defeats as well.