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Pistons vs 76ers Prediction 11/14/25 NBA Picks Today

Philadelphia 76ers (7-4) vs. Detroit Pistons (10-2)
November 14, 2025 7:30 pm EDT
The Line: Detroit Pistons -5.5; Over/Under: 232.5
(Get latest betting odds)

The Philadelphia 76ers and Detroit Pistons meet Friday in NBA action at the Little Caesars Arena. Here’s a Pistons vs 76ers Prediction. This article will include a Pistons vs 76ers Pick.

Philadelphia 76ers Betting Preview

The Philadelphia 76ers lost to the Pistons, beat the Celtics, and they play the Clippers next. The 76ers have split their last 8 games.

The Philadelphia 76ers are averaging 122.4 points on 47.3 percent shooting and allowing 118.5 points on 47.5 percent shooting. Tyrese Maxey is averaging 33.2 points and 8.2 assists, while Joel Embiid is averaging 19.7 points and 5.5 rebounds. Kelly Oubre Jr. is the third double-digit scorer and Quentin Grimes is grabbing 4.1 rebounds. The Philadelphia 76ers are shooting 38.5 percent from beyond the arc and 79.4 percent from the free-throw line. The Philadelphia 76ers are allowing 34.8 percent shooting from deep and are grabbing 43.9 rebounds per game.

Detroit Pistons Betting Preview

The Detroit Pistons beat the Wizards and Bulls, and they play the Pacers next. The Pistons have won 8 straight games.

The Detroit Pistons are averaging 118 points on 46.7 percent shooting and allowing 112.8 points on 43.4 percent shooting. Cade Cunningham is averaging 25.6 points and 4.8 rebounds, while Jalen Duren is averaging 19.2 points and 1.6 assists. Tobias Harris is the third double-digit scorer and Ausar Thompson is grabbing 6.8 rebounds. The Detroit Pistons are shooting 34.2 percent from beyond the arc and 73.4 percent from the free-throw line. The Detroit Pistons are allowing 35.8 percent shooting from deep and are grabbing 48.3 rebounds per game.

Why the Detroit Pistons will win

  • The 76ers have lost each of their last 13 road games against teams that held a winning record.
  • The Pistons have won each of their last eight games.
  • The 76ers have failed to cover the spread in five of their last six games as road underdogs when playing with a rest advantage.
  • The home team has covered the spread in each of the 76ers’ last three games.

Why the Philadelphia 76ers will win

  • The Pistons have lost 13 of their last 14 games against Atlantic Division opponents after winning as underdogs.
  • The 76ers have won 10 of their last 11 games when playing with a rest advantage against the Pistons.
  • The 76ers have covered the spread in 10 of their last 11 games when playing with a rest advantage against the Pistons.
  • The Pistons have failed to cover the spread in eight of their last nine games against 76ers teams that held a winning record.

Total Points Facts

  • Five of the Pistons’ last six home games against Eastern Conference opponents have gone OVER the total points line.
  • Twelve of the 76ers’ last 15 games as road underdogs have gone OVER the total points line.

Pistons vs 76ers Injury Report

The Pistons will be without Jaden Ivey, Marcus Sasser, Isaiah Stewart, Ausar Thompson, Tobias Harris. Cade Cunningham and Jalen Duren are questionable.

The 76ers will be without Paul George and Joel Embiid. VJ Edgecombe is questionable with a back issue.

Pistons vs 76ers Prediction

The Pistons are piling up the wins and are hard to step in front of right now, but they’re also banged up and enter this game with key players on the injury report. The 76ers are 9-1-1 ATS on the season and have not lost bettors money since October 25. The 76ers and Pistons met a few days ago, and it was a three-point loss for Philly, which was another cover. The underdog has covered the last 4 games between the Pistons and 76ers. I’m rolling with the cash cows. Give me the 76ers and the points.

Randy Chambers's Free Pick: Philadelphia 76ers +5.5

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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