Grizzlies vs Spurs Prediction 3/25/26 NBA Picks Today
San Antonio Spurs (54-18) vs. Memphis Grizzlies (24-47)
March 25, 2026 8:00 pm EDT
The Line: Memphis Grizzlies +16.5; Over/Under: 234.5
(Get latest betting odds)
The San Antonio Spurs and Memphis Grizzlies meet Wednesday in NBA action at the FedExForum. Here’s a Grizzlies vs. Spurs Prediction. This article will include a Grizzlies vs. Spurs Pick.
San Antonio Spurs Betting Preview
The San Antonio Spurs beat the Pacers and Heat, and they play the Bucks next. The Spurs have won 27 of their last 33 games.
The San Antonio Spurs are averaging 119 points on 48.1 percent shooting and allowing 111.7 points on 45.1 percent shooting. Victor Wembanyama is averaging 24.3 points and 11.1 rebounds, while De’Aaron Fox is averaging 19 points and 6.3 assists. Stephon Castle is the third double-digit scorer, and Devin Vassell is dishing 2.5 assists. The San Antonio Spurs are shooting 35.9 percent from beyond the arc and 78.4 percent from the free throw line. The San Antonio Spurs are allowing 35.6 percent shooting from deep and are grabbing 46.6 rebounds per game.
Memphis Grizzlies Betting Preview
The Memphis Grizzlies lost to the Hornets and Hawks and play the Rockets next. The Grizzlies have lost 11 of their last 12 games.
The Memphis Grizzlies are averaging 115.7 points on 46 percent shooting and allowing 118.6 points on 47.6 percent shooting. Ty Jerome is averaging 20.2 points and 3.1 rebounds, while Ja Morant is averaging 19.5 points and 8.1 assists. Santi Aldama is the third double-digit scorer, and Cedric Coward is grabbing 6.2 rebounds. The Memphis Grizzlies are shooting 35.5 percent from beyond the arc and 79.2 percent from the free-throw line. The Memphis Grizzlies are allowing 36.1 percent shooting from deep and are grabbing 43.5 rebounds per game.
Why the Memphis Grizzlies will win
- The Grizzlies have won seven of their last eight games against the Spurs following a road loss.
- The Spurs have lost eight of their last 10 games at FedExForum.
- The home team has covered the spread in each of the Grizzlies’ last five games.
- The Spurs have failed to cover the spread in six of their last seven road games against Southwest Division opponents that held a losing record.
Why the San Antonio Spurs will win
- The Spurs have won 22 of their last 23 night games.
- The Grizzlies have lost 11 of their last 12 games.
- The road team has covered the spread in each of the Spurs’ last four games.
- The Grizzlies have failed to cover the spread in four of their last five games following a road loss.
Total Points Facts
- Each of the Grizzlies’ last four games against Southwest Division opponents has gone UNDER the total points line.
- Four of the Spurs’ last five games at FedExForum have gone UNDER the total points line.
Grizzlies vs Spurs Injury Report
The Grizzlies will be without Kentavious Caldwell-Pope, Zach Edey, Ja Morant, Scotty Pippen, Santi Aldama, and Brandon Clarke. Jahmai Mashack is questionable.
David Jones Garcia, De’Aaron Fox, and Luke Kornet are out for the Spurs.
Grizzlies vs Spurs Prediction
The Spurs have the ability to blow the doors off, as the Grizzlies have pretty much shut down their rotation and aren’t trying to win. However, the Spurs can’t be motivated to pour it on. i don’t think it’s a coincidence Kornet and Fox have already been ruled out. This is a win and get out situation. Give some guys some rest. The Grizzlies did upset the Spurs back in January and the guys who are on the court compete. The Grizzlies have covered 33 games. While it’s still not great, the Grizzlies don’t completely roll over like the Wizards or Kings most nights. Give me the endless amount of points with the Grizzlies.

