Memphis Grizzlies (4-10) vs. San Antonio Spurs (9-4)
November 18, 2025 8:00 pm EDT
The Line: San Antonio Spurs -5.5; Over/Under: 233.5
(Get latest betting odds)
The Memphis Grizzlies invade the Frost Bank Arena to take on the San Antonio Spurs on Tuesday night. Here’s a Spurs vs Grizzlies Prediction. This article will include a Spurs vs Grizzlies Pick.
Memphis Grizzlies Betting Preview
The Memphis Grizzlies have been doing it tough lately as they’ve lost eight of their last nine games overall. They will be looking to snap a four-game slide after getting beaten by the Cavaliers in a 108-100 road defeat on Saturday. Jaren Jackson Jr led the team with 26 points on six of 23 shooting, Zach Edey added 13 points, Santi Aldama scored 12 points with 11 rebounds while Cedric Coward chipped in with 10 points but no other player scored more than eight points. As a team, the Grizzlies shot just 36 percent from the field and nine of 32 from the 3-point line as they got off to a quick start. They really took the fight to the Cavaliers in a close contest until the fourth quarter, where the Grizzlies got outscored by 32-16 to spoil a spirited effort. Ja Morant finished with just seven points in six minutes of action, as he left the game in the first quarter with a right calf strain.
San Antonio Spurs Betting Preview
Meanwhile, the San Antonio Spurs have been in pretty good form as they’ve won four of their past six games and they will be eager to keep it going after blowing past the Kings in a 123-110 home win on Sunday. De’Aaron Fox led the team with 28 points and 11 assists on 11 of 20 shooting, Harrison Barnes added 20 points on seven of 11 shooting, Devin Vassell scored 16 points with seven assists while Keldon Johnson chipped in with 14 points and 12 rebounds. As a team, the Spurs shot 54 percent from the field and 14 of 38 from the 3-point line as they set the tone with 36 points in the first quarter to jump out in front. They were never really in danger in a game where they led by as many as 19 points at one stage.
Why the San Antonio Spurs will win
- The Grizzlies have lost each of their last 15 games against Western Conference opponents that held a winning record.
- The favorites have won each of the Grizzlies’ last 12 games.
- The Grizzlies have failed to cover the spread in eight of their last nine games as underdogs.
- The favorites have covered the spread in eight of the Grizzlies’ last nine games.
Why the Memphis Grizzlies will win
- The Grizzlies have won each of their last 11 road games against the Spurs.
- The Spurs have lost 14 of their last 15 home games against Southwest Division opponents following a win.
- The Spurs have failed to cover the spread in each of their last six games as favorites against Southwest Division opponents following a win.
- The road team has covered the spread in seven of the last eight games between the Grizzlies and Spurs.
Total Points Facts
- Seven of the Spurs’ last eight home games against Southwest Division opponents have gone OVER the total points line.
- Each of the Grizzlies’ last five games as underdogs following a road loss have gone UNDER the total points line.
San Antonio Spurs Player Facts
- Keldon Johnson ranks 1st amongst qualified Guards for FG% (55.8%) this season.
- Harrison Barnes is one of only three qualified players in the league shooting at least 50% from the field, 40% from three and 90% from the free-throw line this season.
Memphis Grizzlies Player Facts
- Cam Spencer has recorded seven games with 2+ assists and zero turnovers this season – most of any player in the league.
- Jaren Jackson Jr. is one of only two players in the league to have recorded 6+ blocks in a game this season.
Matchup/League Facts
- The Spurs rank 1st in the league for opponent blocks per game this season (3.5).
- The Spurs rank 1st in the league for Q1 opponent points per game this season (25.1).
- The Grizzlies rank 29th in the league for field goal percentage this season (43.0%).
- The Grizzlies rank 29th in the league for effective field goal percentage this season (50.2%).
Spurs vs Grizzlies Prediction
The Grizzlies have ruled out Ja Morant, Ty Jerome, Javon Small and Brandon Clarke, while the Spurs are missing Stephon Castle, Dylan Harper and Victor Wembenyama. Both teams are missing some key players for this one, but it’s the Spurs who have looked better so far, as they were still good enough to take down the Kings on Sunday. Sure, the Grizzlies were always underdogs against the Cavaliers in their last game, but they eventually got found out once the game got close. I think we are in for a good contest here, but the Spurs have clearly been the team in better form, and I think they can get the job done at home in this one.
