San Francisco 49ers vs Kansas City Chiefs Prediction 10-20-24 NFL Picks

The Kansas City Chiefs and the San Francisco 49ers meet in week 7 NFL action from Levi’s Stadium on Sunday afternoon. We will look at this from a betting perspective and determine the best bets for this game. Here’s a San Francisco 49ers vs Kansas City Chiefs Prediction.

Kansas City Chiefs Recap

The Kansas City Chiefs come into this one looking to keep the ball rolling after their bye week thanks to a 26-13 win over the New Orleans Saints in their last matchup to improve to 5-0 on the year. After this game, the Chiefs will head out on the road for a matchup against the Las Vegas Raiders.

Chiefs Trying To Stay Unbeaten

Patrick Mahomes has thrown for 1,235 yards, 6 touchdowns, and 6 interceptions on 69.4% passing while Kareem Hunt has rushed for 171 yards and a touchdown. Rashee Rice leads the Chiefs’ receiving group with 24 grabs for 288 yards and 2 touchdowns this season. Travis Kelce has 24 grabs of his own for 228 yards while three more Chiefs have 100+ receiving yards on the year. On defense, Nick Bolton has a team-high 38 total tackles including 25 solo tackles while Chris Jones has a team-high 3 sacks and the Chiefs’ defense as a whole has combined for 9 sacks and 2 interceptions.

Why the Kansas City Chiefs will win

• The Chiefs have won each of their last 14 games played on the West Coast.
• The 49ers have lost each of their last five October games as favorites against AFC opponents.
• The 49ers have failed to cover the spread in each of their last seven games as favorites against AFC West opponents.
• The Chiefs have covered the spread in each of their last seven games as underdogs.

San Francisco 49ers Recap

The San Francisco 49ers come into this one looking to build on their 36-24 win over the Seattle Seahawks last time out. After this game, the 49ers will welcome the Dallas Cowboys to town.

49ers Looking For Super Bowl Revenge

Brock Purdy has thrown for 1,629 yards, 9 touchdowns, and 4 interceptions on 65.4% passing while Jordan Mason’s rushed for 609 yards and 3 touchdowns on the year. Jauan Jennings has 25 receptions for 404 yards and 3 touchdowns while Brandon Aiyuk has 23 grabs for 351 yards. Deebo Samuel has 335 receiving yards and George Kittle leads the Chiefs in receptions, with Kittle logging 28 grabs for 283 yards with 5 touchdowns. On defense, Fred Warner has a team-high 50 total tackles including 30 solo tackles and 2 interceptions while Nick Bosa has 3 sacks and Kevin Givens has a team-high 3.5 sacks. As a unit, San Francisco’s defense has combined for 16 sacks and 6 interceptions so far this season.

Why the San Francisco 49ers will win

• The 49ers have won 13 of their last 14 games following a Division game.
• The 49ers have covered the spread in eight of their last nine games following a Division win.

San Francisco 49ers vs Kansas City Chiefs Prediction

I’m going to back the Chiefs here. I was initially on the 49ers earlier in the week, but the more I look at it, Andy Reid has been fantastic off of a bye week, Patrick Mahomes is money as an underdog, and I think this would’ve been a bigger must-win spot if the Niners had lost last week. I’m not saying they don’t come out with any less intensity, but getting points with the Chiefs is not something that’s going to happen every day and I think that the Chiefs, while they’ve been winning a lot of close games, could get another one here. Give me the Chiefs and the points. *UPDATED Oct 19/24 @ 7:05 PM*