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Trail Blazers vs Thunder Prediction 11/5/25 NBA Picks Today

Oklahoma City Thunder (7-0) vs. Portland Trailblazers (4-3)
November 5, 2025 10:00 pm EDT
The Line: Portland Trailblazers +5.5; Over/Under: 228.5
(Get latest betting odds)

The Oklahoma City Thunder invade the Moda Center to take on the Portland Trail Blazers on Wednesday night. Here’s a Trail Blazers vs Thunder Prediction. This article will include a Trail Blazers vs Thunder Pick.

Oklahoma City Thunder Betting Preview

The Oklahoma City Thunder have kicked off their season with eight wins in a row and they will be brimming with confidence following last night’s 126-107 win over the Clippers. Shai Gilgeous-Alexander led the team with 30 points and 12 assists on nine of 14 shooting, Isaiah Joe added 22 points off the bench while Cason Wallace chipped in with 12 points.
As a team, the Thunder shot 52 percent from the field and 18 of 38 from the 3-point line as they overcame a slow start. They dominated the second half by 70-50 to blow away the Clippers after trailing by as many as 13 points early on.

Portland Trail Blazers Betting Preview

Meanwhile, the Portland Trail Blazers were starting to heat up with three wins in a row before they got stopped by the depleted Lakers in a 123-115 home defeat on Monday. Deni Avdija led the team with 33 points on 10 of 20 shooting, Shaedon Sharpe added 23 points while Jerami Grant chipped in with 18 points and four assists off the bench.
As a team, the Trail Blazers shot 49 percent from the field and nine of 40 from the 3-point line as they jumped out to an early double digit lead. But they allowed the Lakers to hang around, and it cost them in the second half where they leaked 71 points to end up on the wrong side of the scoreboard. The Trail Blazers could’ve done with more production from Jrue Holiday who finished with just eight points on four of 11 shooting.

Trail Blazers vs Thunder Prediction

The Thunder are still missing Jalen Williams, Kenrich Williams and Nikola Topic, while the Trail Blazers are still missing Scoot Henderson, Matisse Thybulle and Blake Wesley. The Thunder have been the benchmark of the league since opening night, and it doesn’t look like they are slowing down if you saw their win over the Clippers last night. The Trail Blazers were building some nice momentum themselves before they lost their focus against a shorthanded Lakers squad in their last game, so they might like their chances here. The Thunder’s perfect start to the season has to come to an end eventually, but with the line so short, I can’t resist another play on the Thunder, who have won their last three by double digits.

Peter Tran's Free Pick: Oklahoma City -5.5

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Peter Tran

Peter Trans is an acclaimed Expert NBA Handicapper, renowned for his insightful analysis and predictions in the world of professional basketball. With a keen eye for detail and a deep understanding of the game, Peter has established himself as a trusted authority among basketball enthusiasts and bettors alike. His expertise is showcased on SportsChatPlace.com, where he provides in-depth game analyses, betting tips, and forecasts that are both highly informative and remarkably accurate.

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